Table 2.
The odds ratio of interstitial cystitis/bladder pain syndrome by time-varying defined variable.
| Odds Ratio (95% CI) by Different Time Windows before Index Date | ||||
|---|---|---|---|---|
| −24 to −12 Months | −12 to −6 Months | −6 to −3 Months | −3 Months to Index | |
| Comorbidities | ||||
| UTI | 6.45 (5.46 to 7.63) | 8.27 (6.89 to 9.93) | 13.11 (10.29 to 16.69) | 21.39 (17.05 to 26.84) |
| COPD | 1.90 (1.49 to 2.43) | 2.12 (1.59 to 2.81) | 1.77 (1.23 to 2.54) | 2.19 (1.54 to 3.12) |
| Peptic ulcer | 2.72 (2.26 to 3.26) | 3.38 (2.74 to 4.16) | 2.68 (2.09 to 3.42) | 3.48 (2.73 to 4.42) |
| IBS | 1.60 (0.87 to 2.92) | 3.25 (1.56 to 6.76) | 2.86 (0.91 to 9.00) | 4.00 (1.67 to 9.61) |
| Autoimmune disease | 1.27 (0.95 to 1.68) | 1.96 (1.44 to 2.66) | 1.59 (1.12 to 2.27) | 1.75 (1.22 to 2.49) |
| Depression | 2.39 (2.00 to 2.85) | 3.15 (2.58 to 3.83) | 2.71 (2.18 to 3.37) | 3.79 (3.06 to 4.69) |
| Sleep disorders | 2.32 (1.96 to 2.75) | 2.39 (1.98 to 2.89) | 2.12 (1.71 to 2.61) | 2.63 (2.13 to 3.24) |
| Asthma | 1.57 (1.15 to 2.16) | 1.45 (0.98 to 2.14) | 1.52 (0.96 to 2.41) | 2.08 (1.30 to 3.32) |
| Allergic rhinitis | 1.68 (1.36 to 2.07) | 1.51 (1.16 to 1.95) | 1.92 (1.42 to 2.61) | 1.95 (1.42 to 2.68) |
| Atopic dermatitis | 1.62 (1.03 to 2.55) | 1.13 (0.61 to 2.10) | 3.20 (1.26 to 8.11) | 2.26 (1.15 to 4.46) |
IC/BPS, interstitial cystitis/bladder pain syndrome; UTI, urinary tract infection; COPD, chronic obstructive pulmonary disease; IBS, irritable bowel syndrome.