Table A2.

Study definitions.

Study Definitions
Hemorrhage in the Emergency Department Objective bleeding in the emergency department within the first 4 h of presentation. This definition does not include blood on the glove after digital rectal examination.
Shock
Heart rate (HR) of >100/min associated with systolic blood pressure (SBP) of <100 mmHg
Major hemorrhage
Bleeding leading to SBP of <90 mmHg or HR of >110/min
Appropriate threshold for blood transfusion
Hemoglobin (Hb) < 7.0 g/dl in patients without major hemorrhage (see above) or major comorbidity (mainly cardiovascular). For these two situations, a threshold of Hb < 9.0 g/dl was considered adequate.
In-hospital mortality
Any cause of death during the patient’s stay
Intervention
Blood transfusion, endoscopic hemostasis, embolization by interventional radiology or surgery