APC |
antigen-presenting cell |
BSA |
bovine serum albumin |
CD |
cluster of differentiation |
CDK |
cyclin-dependent kinase |
CST |
Cell Signaling Technologies |
DAB 3,3’ |
diaminobenzidine |
DDRD |
DNA damage response is deficient |
DMEM |
Dulbecco’s modified Eagle’s medium |
DMSO |
dimethyl sulfoxide |
EDTA |
ethylenediaminetetraacetic acid |
FACS |
fluorescence-activated cell scanning |
FCS |
fetal calf serum |
HNSCC |
head and neck squamous cell carcinoma |
HPV |
human papillomavirus |
HRP |
horseradish peroxidase |
IC50
|
half maximal inhibitory concentration |
IgG |
immunoglobulin G |
KD |
knockdown |
M phase |
mitosis phase |
mAb |
monoclonal antibody |
MDSC |
myeloid-derived suppressor cells |
MEF |
mouse embryonic fibroblast |
MTT |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide |
nM |
millimolar |
ns |
not significant |
NT |
non-targeting |
ORR |
overall response rate |
pAb |
polyclonal antibody |
PBS |
phosphate-buffered saline |
PCI |
Pittsburgh Cancer Institute |
PCR |
polymerase chain reaction |
PD-1 |
programmed cell death protein-1 |
PD-L1 |
programmed cell death ligand-1 |
PE |
phycoerythrin |
PFA |
paraformaldehyde |
RB |
retinoblastoma |
RT |
room temperature |
S phase |
synthesis phase |
SD |
standard deviation |
SDS-PAGE |
sodium dodecyl sulfate polyacrylamide gel electrophoresis |
siRNA |
small interfering ribonucleic acid |
SPOP |
speckle-type POZ protein |
TIL |
tumor-infiltrating lymphocyte |
Tregs |
regulatory T cells |
WAPL |
wing apart-like |
WB |
Western blot |