Table 2.
Clinical and pathological stage, type of surgery and structures resected, dosage of intraoperative cisplatin and post-operative results.
| Variable | n (%) | Median (Range) |
|---|---|---|
| Side | ||
| Right | 8 (66.6%) | |
| Left | 4 (33.3%) | |
| Structures clinically involved | ||
| P | 4 (33.3%) | |
| P, D | 3 (25%) | |
| P, V | 2 (16.6%) | |
| P, V, D | 1 (8.4%) | |
| P, V, D, Pe | 2 (16.6%) | |
| Staging TNM | ||
| cT1N0M0 | 5 (41.6%) | |
| cT2N0M0 | 6 (50%) | |
| cT3N0M0 | 1 (8.4%) | |
| Clinical stage | ||
| IA | 5 (41.6%) | |
| IB | 7 (58.4%) | |
| Type of NAC | ||
| CDDP + pemetrexed | 5 (41.6%) | |
| CBDCA + pemetrexed | 7 (58.4%) | |
| Type of surgery/structures resected | ||
| P/D | 6 (50%) | |
| eP/D diaphragm | 3 (25%) | |
| eP/D pericardium | 2 (16.6%) | |
| eP/D diaphragm+pericardium | 1 (8.4%) | |
| Cisplatin dosage | 150 mg/mq | 100–150 mg/mq |
| Pathological involvement | ||
| CR | 1 (8.4%) | |
| Major pathological response, P | 1 (8.4%) | |
| Major pathological response, V | 1 (8.4%) | |
| P, V | 1 (8.4%) | |
| P, V, D | 2 (16.6%) | |
| P, V, D, Pe | 2 (16.6%) | |
| P, V, lung, ln5 | 1 (8.4%) | |
| P, V, D, Pe, lung | 2 (16.6%) | |
| P, V, D, lung, pericardial fat | 1 (8.4%) | |
| pTNM | ||
| CR | 1 (8.4%) | |
| pT1N0M0 | 3 (25%) | |
| pT3N0M0 | 7 (58.4%) | |
| pT3N1M0 | 1 (8.4%) | |
| Pathological stage | ||
| CR | 1 (8.4%) | |
| IA | 3 (25%) | |
| IB | 7 (58.4%) | |
| IIIA | 1 (8.4%) | |
| ICU stay | 2 days | 1–7 days |
| Hospital stay | 10.5 days | 6–20 days |
| Complications in detail | ||
| Blood transfusion | 5 (58.4%) | |
| Prolonged air leak | 3 (25%) | |
| Chylothorax | 3 (25%) | |
| Bleeding requiring surgery | 1 (8.4%) | |
| Post-operative re-habilitation | 2 (16.6%) | |
| Chronic pain | 1 (8.4%) | |
| Recurrence | ||
| No recurrence | 3 (25%) | |
| Local | 6 (50%) | |
| Local and distant | 3 (25%) |
P: Parietal; V: Visceral; D: Diaphragm; Pe: Pericardium; TNM: Tumor, Node and Metastasis; NAC: Neoadjuvant therapy; CBDCA: carboplatinum; CDDP: cisplatinum; P/D: pleurectomy and decortication; eP/D: extended pleurectomy and decortication; ln5: lymph node station 5; CR: Complete pathological Response; ICU: Intensive Care Unit.