Table 1.

Characteristics of the top five most studied tumor hepatic cell lines.

	Cell Type	Mutated Genes	Number of Chromosomes	Number of Articles (PubMed)	Reference
HepG2	HB	CTNNB1	50–60	34,021	[12,30]
HepaRG	HCC	PLIN2, ANXA1, H2AFY, SNX1, GCHFR, APO	46	880	[26,31,32,33]
Huh7	HCC	KDR, POLD3, TERT, TP53	55–63	6463	[34,35,36,37]
Hep3B	HCC	AXIN1, RB1	≈60	2994	[34,38]
SK-Hep-1	Adenocarcinoma	CDKN2A, BRAF	56–64	602	[39,40]