Table 1.
Baseline patient characteristics.
| Total Population (n = 432) |
LVEF > 40% (n = 335, 78%) |
LVEF ≤ 40% (n = 97, 22%) |
p-Value | |
|---|---|---|---|---|
| Age, years | 57 [51–65] | 56 [50–64] | 58 [53–69] | 0.010 |
| Female, n (%) | 81(19) | 68 (20) | 13 (13) | 0.125 |
| Body mass index, kg/m2 | 26.1 [24.4–28.7] | 26.0 [24.4–28.7] | 26.2 [24.7–28.7] | 0.622 |
| Current smoker, n (%) | 247 (57) | 205 (61) | 42 (43) | 0.002 |
| Hyperlipidemia, n (%) | 230 (53) | 176 (53) | 54 (56) | 0.586 |
| Diabetes mellitus, n (%) | 35 (8) | 25 (8) | 10 (10) | 0.366 |
| Family history, n (%) | 135 (31) | 112 (33) | 23 (24) | 0.160 |
| Hypertension, n (%) | 191 (44) | 148 (44) | 43 (44) | 0.979 |
| Systolic blood pressure, mmHg | 137 [117–154] | 136 [117–154] | 137 [118–152] | 0.827 |
| Diastolic blood pressure, mmHg | 82 [72–95] | 80 [72–94] | 85 [76–100] | 0.039 |
| Symptomatic heart failure before STEMI, n (%) | 0 (0) | 0 (0) | 0 (0) | - |
| Killip class, n (%) | <0.001 | |||
| I | 296 (69) | 247 (74) | 49 (50) | |
| II | 136 (32) | 88 (26) | 48 (50) | |
| Total ischemia time, min | 178 [120–262] | 171 [120–260] | 188 [129–267] | 0.407 |
| Culprit lesion, n (%) | <0.001 | |||
| RCA | 183 (42) | 165 (49) | 18 (19) | |
| LAD | 189 (44) | 124 (37) | 65 (67) | |
| LCX | 57 (13) | 45 (13) | 12 (12) | |
| RI | 3 (1) | 1 (1) | 2 (2) | |
| Anterior infarction, n (%) | 190 (44) | 126 (38) | 64 (66) | <0.001 |
| Number of affected vessels, n (%) | 0.656 | |||
| 1 | 260 (60) | 201 (60) | 59 (61) | |
| 2 | 119 (28) | 95 (28) | 24 (25) | |
| 3 | 53 (12) | 39 (12) | 14 (14) | |
| TIMI flow pre-PCI, n (%) | 0.018 | |||
| 0 | 273 (63) | 200 (60) | 73 (75) | |
| 1 | 55 (13) | 43 (13) | 12 (13) | |
| 2 | 75 (17) | 67 (20) | 8 (8) | |
| 3 | 29 (7) | 25 (7) | 4 (4) | |
| TIMI flow post-PCI, n (%) | 0.006 | |||
| 0 | 4 (1) | 2 (1) | 2 (2) | |
| 1 | 6 (1) | 3 (1) | 3 (3) | |
| 2 | 34 (8) | 20 (6) | 14 (14) | |
| 3 | 388 (90) | 310 (92) | 78 (81) | |
| CRP, mg/L | ||||
| Admission | 2.1 [1.0–4.2] | 2.0 [1.0–4.2] | 2.3 [1.0–4.7] | 0.383 |
| 24 h | 12.4 [6.9–20.1] | 11.0 [6.0–17.1] | 20.9 [10.9–45.7] | <0.001 |
| Peak | 22.5 [11.7–45.5] | 19.0 [10.3–34.4] | 54.6 [25.9–94.7] | <0.001 |
| Admission to 24 h CRP, h | 21 [19–25] | 21 [19–25] | 21 [19–25] | 0.640 |
| Admission to peak CRP, h | 46 [35–56] | 45 [31–55] | 47 [42–58] | 0.028 |
| CRPv (admission to 24 h), mg/L/h | 0.42 [0.21–0.76] | 0.34 [0.16–0.61] | 0.81 [0.47–1.78] | <0.001 |
| cTnT, ng/L | ||||
| Peak | 4646 [2187–8430] | 3902 [1718–6676] | 9065 [5014–14877] | <0.001 |
| Admission to peak cTnT, h | 11 [7–16] | 11 [7–16] | 9 [6–13] | 0.014 |
CRP = C-reactive protein, CRPv = C-reactive protein velocity, cTnT = cardiac troponin T, LAD = left anterior descending artery, LCX = left circumflex artery, LVEF = left ventricular ejection fraction, PCI = percutaneous coronary intervention, RCA = right coronary artery, RI = ramus intermedius, TIMI = thrombolysis in myocardial infarction.