Table 3.
Half maximal Cdk2/cyclin A inhibitory concentration (IC50) values of p27-KID variants using Histone H1 as substrate.
| P27-KID- | IC50(nM) |
|---|---|
| WT | 1.9 ± 0.3 |
| W60A | 1.7 ± 0.3 |
| W76A | 4.3 ± 1 |
| W60A-W76A | 36 ± 8 |
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