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In vitro anti-proliferative activities of representative compounds against MM.1S cell line.
| Comp. | IC50 a (μM ± SD) |
|---|---|
| 9b | >10 |
| 9e | >10 |
| 15a | >10 |
| 15d | >10 |
| 21a | 0.043 ± 0.020 |
| 21b | 0.541 ± 0.108 |
| 23a | >10 |
| 23b | 1.34 ± 0.40 |
| SAHA b | 0.20 ± 0.03 |
a Data are the mean ± SD value of three independent determinations. b Positive control.
