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. 2021 Nov 28;26(23):7216. doi: 10.3390/molecules26237216

Table 3.

Activity of cannabinoids and C. sativa against fungi.

Pathogen Compound/Extract/EO Activity Reference Antibiotic Ref
Antibiotic Activity
Candida albicans Extract MIC 0.25 mg/mL [124]
C. albicans Extract MIC 1.42 mg/mL Fluconazole MIC 2 mg/mL [99]
C. albicans 4-terpenyl cannabinolate MIC 8.5 µg/mL [125]
C. albicans 8-hydroxycannabinol IC50 4.6 µM Amphotericin B IC50 0.3 µM [96]
C. albicans Cannabis and ginger blend MIC 4.69 mg/mL [126]
C. albicans CBDV IC50 11.9 mM Nystatin IC50 1.50 mM [97]
C. albicans CBNA IC50 8.5 µg/mL [125]
Candida krusei Cannabinoids IC50 53.4–60.5 µM amphotericin B IC50 0.7 µM [96]
Candida neoformans β-caryophyllene/oxide IC50 1.18–19.4 µg/mL [98]
Candida species β-caryophyllene MIC 1.45–10.0 µg/mL [98]
Plasmodium falciparum Cannabinoids IC50 4.0–6.7 µM Chloroquine IC50 0.1–0.5 µM [96]
P. falciparum CBNA IC50 2.4–2.7 µg/mL [125]
Trichophyton and Arthroderma species EO MIC 0.312–6.3 µg/mL Griseofulvin MIC 1.26 to >8.0 µg/mL [123]