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. 2021 Nov 28;26(23):7208. doi: 10.3390/molecules26237208

Figure 2.

Figure 2

Impact of antifungal compounds 2b, 3b and amorolfine hydrochloride (A) on the survival of Galleria mellonella larvae. The Kaplan Meyer curves represent average survival rates of 40 larvae per sample (2 independent experiments). Each larva was injected with 20 µL of the respective antifungal solution, and dilutions were made in PBS. Untouched larvae and larvae injected with PBS served as controls. Test compound concentration was chosen according to MIC data: 100 µM represents the MIC/g larvae for 2b and 3b; 500 µM, the MIC for amorolfine hydrochloride; and 1000 µM 10-fold, the MIC of 2b and 3b.