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. 2000 May;38(5):1791–1796. doi: 10.1128/jcm.38.5.1791-1796.2000

TABLE 1.

Isoelectric points and susceptibilities of AmpC-producing isolates

Isolate pIa MICb (μg/μl)
AMP FOX FOX-Ro(4) CPD CPD-Cl(4) CRO CRO-Cl(2) CTX CAZ AZT CEF IMI
E. coli
 M477 9.1 256 32 8 128 128 16 16 8 128 16 4 0.13
 M491 9.1 512 64 16 128 128 4 4 8 32 16 0.13 0.13
 M483 9.1 512 32 8 512 256 16 16 16 64 16 0.5 0.13
 M540 9.0, 5.4 4,096 128 32 128 128 2 1 4 4 16 0.13 0.06
 M545B 9.0 512 64 16 128 64 1 1 4 4 16 0.06 0.06
M563c 9.1 265 32 2 128 64 1 0.5 2 4 8 0.03 0.13
 M656 9.1 64 8 2 8 4 0.13 0.13 0.5 0.5 1 0.06 0.13
 M683 9.0 64 8 2 8 8 0.13 0.06 0.5 0.5 1 0.02 0.06
M752 7.2, 5.6 >4,096 64 32 128 128 2 2 8 32 1 0.06 0.13
 M804 9.0 256 32 4 128 64 1 0.5 2 2 2 0.03 0.13
M809 9.0 512 128 4 512 512 32 32 16 32 16 0.13 0.13
K. pneumoniae
M484 7.2, 5.6 >4,096 1,024 1,024 2,048 2,048 64 32 32 256 8 4 1.0
M621 7.2, 5.6, 7.8 >4,096 64 64 128 128 8 4 16 64 16 0.25 0.13
M625B 7.2, 5.6, 7.8 >4,096 128 64 256 128 8 4 8 64 32 0.5 0.13
M846 7.2, 5.6 >4,096 64 64 256 256 8 8 16 64 4 0.5 0.25
P. mirabilisM910 9.0 128 16 2 256 256 2 2 4 1 0.25 0.13 4.0
a

The first isoelectric points correspond to those for the cloxacillin-inhibited band (AmpC); additional pIs correspond to those for clavulanic acid-inhibited bands. 

b

AMP, ampicillin; FOX, cefoxitin; FOX-Ro(4), cefoxitin plus 4 μg of Ro 48-1220 per ml; CPD, cefpodoxime; CPD-Cl(4), cefpodoxime plus 4 μg of clavulanic acid per ml; CRO, ceftriaxone; CRO-Cl(2), ceftriaxone plus 2 μg clavulanic acid per ml; CTX, cefotaxime; CAZ, ceftazidime; AZT, aztreonam; CEF, cefepime; IMI, imipenem. 

c

Resistance was transferred for the underlined isolates.