Table 3.

Nanocurcumin in clinical trial studies.

S. No.	Clinical Studies Identifier	Study Title	Interventions	Phase, Recruitment Status	Place Intended for Study	References
1	IRCT2017080135444N1	The synergistic effects of nanocurcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial	Migraine-related impairment	Phase 2 and 3, completed	Tehran University of Medical Sciences, Tehran, Iran	[216]
2	NCT02532023	Effects of nanocurcumin on inflammatory factors and clinical outcomes in critically ill patients with sepsis: A pilot randomized clinical trial	Patients with sepsis who are severely sick	Phase 4, completed	Tabriz University of Medical Sciences, Tabriz, Iran	[217]
3	IRCT20200705048018N1	The effects of nanocurcumin as a nutritional strategy on clinical and inflammatory factors in children with cystic fibrosis: the study protocol for a randomized controlled trial	Cystic fibrosis	Phase 1, Recruiting	Akbar Children’s Hospital, Mashhad, Iran.	[218]
4	IRCT20161208031300N1	Impact of resistance exercises and nanocurcumin on synovial levels of collagenase and nitric oxide in women with knee osteoarthritis	Osteoarthritis	Phase 3, completed	Imam Ali Hospital, Bojnourd, Iran	[219]
5	IRCT20190523043678N1	Combination Therapy with 1% Nanocurcumin Gel and 0.1% Triamcinolone Acetonide Mouth Rinse for Oral Lichen Planus: A Randomized Double-Blind Placebo Controlled Clinical Trial	Oral lichen planus	Phase 3, completed	Shahid Beheshti University of Medical Sciences, Iran	[220]
6	NCT03150966	The immunomodulatory effects of oral nanocurcumin in multiple sclerosis patients	Multiple sclerosis	Phase 2, completed	Tabriz University of Medical Sciences, Iran	[221]
7	NCT01201694	Study on surface controlled water soluble curcumin	Cancer	Phase 1, completed	UT MD Anderson Cancer Center Houston, Texas, United States	[222]