BCR |
B-cell receptor |
BTK |
Bruton’s kinase |
BTKIs |
BTK inhibitors |
CLL |
lymphocytic leukemia |
CIA |
collagen-induced arthritis |
DPPY |
diphenylaminopyrimidine |
EGFR |
epidermal growth factor receptor |
FAK |
focal adgesion kinase |
FBDD |
fragment-based drug discovery |
cGVHD |
chronic graft versus host disease |
MZL |
marginal zone lymphoma |
MCL |
mantle cell lymphoma |
MS |
multiple scherosis |
NSCLC |
non-small cell lung cancer |
PMDA |
Pharmaceuticals and Medical Devices Agency |
PH |
pleckstrin homology domain |
Pho-DPYYs |
diphenylpyrimidine derivatives |
PLCγ2 |
phospholipase γ2 |
PK |
pharmacokinetic |
PROTAC |
proteolysis-targeting chimera compounds |
PRR |
proline-rich regions |
RA |
rheumatoid arthritis |
RMS |
Relapsing Multiple Sclerosis |
ROS |
reactive oxygen species |
SBD |
structure-based design |
SLL |
small lymphocytic lymphoma |
SH2/SH3 |
Src homology 2/3 domain |
SLE |
Systemic Lupus Erythematosus |
TK |
tyrosine kinases |
WM |
Waldenström’s macroglobulinemia |
WT |
wild type |