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. 2021 Dec 9;16(12):e0261052. doi: 10.1371/journal.pone.0261052

Table 2. Comparison between OCTAVA and manual calculation of metrics.

Microfluidic device Simulated OCTA MIP
Metric (unit) OCTAVA Manual Relative difference (%) OCTAVA Manual Relative difference (%)
Vessel area density (%) 54 54 0 13 14 7
Vessel length density (%) 2.16 2.16 0 1.1 1.1 0
Mean diameter (μm) 185 169 9 113 110 3
Median diameter (μm) 90 88 2 78 70 11
Branchpoint density (nodes/mm) 1.6 1.7 6 0.27 0.27 0
Fractal dimension 1.35±0.36 1.22±0.36
Mean tortuosity 0.07 0.15