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. 2021 Nov 29;15(11):e0010002. doi: 10.1371/journal.pntd.0010002

Table 3. Immunogenicity of fractional-dose yellow fever vaccine (YFV) in autoimmune rheumatic diseases patients and controls.

Seroprotection rate, n (%) GMT, value (95% CI) Seroconversion rate, n (%) GMT Factor Increase, value (95% CI)
Before YFV After YFV Before YFV After YFV
ARD (n = 149) 6/149 (4.0) * 124/147† (84.3) * 31.2 * (27.6–35.1) 731.0 * (593.6–900.2) 118/141 (83.7) * 23.5 (18.5–29.7)
Controls (n = 148) 21/148 (14.2) 135/140 (96.4) 45.3 (39–52.6) 1143.7 (1012.3–1292.2) 116/120 (96.6) 25.3 (20.6–31)

* p<0.05. Comparison between patients (ARD) and controls

†The samples of 8 controls and 2 ARD patients had indeterminated result of neutralizing antibodies titer measurement at D30.

ARD—autoimmune rheumatic diseases; CI- confidence interval