Table 1.
Phase II, Phase II/III and Phase III CTIMP assessing potential disease-modifying treatment in amyotrophic lateral sclerosis registered, completed or published from 1 January 2008 onwards excluding extension trials according to status, phase and trial design
| Description | Number of trials |
|---|---|
| By status | |
| Active | 35 |
| Completed, has results | 61 |
| Completed, no results | 12 |
| Not yet recruiting | 5 |
| Terminated | 6 |
| Unknown | 4 |
| Withdrawn | 2 |
| Total | 125 |
| By phase | |
| Phase II | 97 |
| Phase II/III | 8 |
| Phase III | 20 |
| Total | 125 |
| By trial design | |
| Non-randomized, open label | 26 |
| Randomized | 96 |
| Parallel: 87 | |
| Crossover: 7 | |
| Factorial: 1 | |
| Assignment not specified: 1 | |
| Parallel, randomization not specified | 1 |
| Not specified | 2 |
| Total | 125 |