Table 5. Half-Maximum Inhibitory Concentrationsa (IC50, μM) of Compounds 1I2Me and 2I2 and their Chlorido Counterparts, Respectively [RuCl2(η6-methyl benzoate)(dimethyl(1-pyrenyl)phosphane)] (1Cl2Me) and [RuCl2(η6-p-cymene)(dimethyl(1-pyrenyl)phosphane)] (2Cl2),35 for A549 (Lung Adenocarcinoma), SW620 (Colorectal Adenocarcinoma) and MCF7 (Breast Carcinoma) Human Cells, after Incubation for 24 h.
| compound | A549 | SW620 | MCF7 |
|---|---|---|---|
| 1I2Me | 2.6 ± 0.4 | 9 ± 2 | 6 ± 1 |
| 1Cl2Meb | 5.0 ± 0.6 | 1.9 ± 0.1 | 5.1 ± 1.6 |
| 2I2Me | 6.3 ± 0.4 | 16 ± 4 | 17 ± 6 |
| 2Cl2Meb | 17.2 ± 0.5 | 6.5 ± 0.8 | 9.7 ± 0.1 |
a
The results are expressed as mean values ± SD out of three independent experiments.
b
Compounds described in ref (35).