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. 2021 Aug 23;1(4):100054. doi: 10.1016/j.xjidi.2021.100054

Figure 13.

Figure 13

Introduction of TSG-6+/+ cells in TSG-6–/– RHE can rescue HA leakage. Schematic representation of TSG-6–/– rescue test: epidermis were reconstructed from different ratios of TSG-6+/+ (green) and TSG-6–/– (red) KCs. HA released in the culture medium of epidermis reconstructed from mixtures of KCs TSG-6+/+ and TSG-6–/– (a) or TSG-6–/– (b) was measured by ELISA-like assay (mean ± SD; n = 3; two-way ANOVA; ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001 vs. TSG-6+/+ 100%). CTL, control; HA, hyaluronan; KC, kerationcyte; RHE, reconstructed human epidermis.