Table 5.
Summary of the Number of Petechiae in Verruca Vulgaris Lesions in Each Subgroup
| FIT039 (n = 13) | Placebo (n = 11) | Group Comparison | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Time Point | n | n1 | Mean (SD) | Change from Day 1 (95% CI) (%) | n | n1 | Mean (SD) | Change from Day 1 (95% CI) (%) | Difference in Change from Day 1 (95% CI) (%) | P-Value |
| Day 1 | 13 | 7 | 15.35 (24.16) | N/A | 11 | 9 | 9.68 (11.41) | N/A | N/A | N/A |
| Day 8 | 13 | 7 | 10.04 (16.15) | 59.04 (20.92–97.16) | 11 | 9 | 5.45 (8.84) | 71.56 (5.16–137.96) | –12.51 (–88.88 to 63.86) | 0.731 |
| Day 15 | 13 | 7 | 8.65 (12.97) | 65.24 (3.87–126.61) | 11 | 9 | 3.32 (4.83) | 28.96 (4.93–52.99) | 36.28 (–17.17 to 89.73) | 0.168 |
| Day 29 | 13 | 7 | 15.42 (30.13) | 66.10 (17.00–115.20) | 11 | 9 | 4.59 (6.63) | 66.76 (–2.58 to 136.10) | –0.66 (–83.38 to 82.06) | 0.987 |
| Day 43 | 13 | 7 | 12.81 (23.62) | 66.58 (27.56–105.61) | 11 | 9 | 6.00 (8.93) | 91.12 (–12.11 to 194.35) | –24.54 (–138.26 to 89.18) | 0.651 |
| Day 57 | 13 | 7 | 11.27 (19.14) | 66.09 (17.55–114.63) | 11 | 9 | 5.77 (8.79) | 51.91 (19.05–84.78) | 14.18 (–35.81 to 65.16) | 0.560 |
Abbreviations: CI, confidence interval; N/A, not applicable.
Change from day 1 (%) = ([value at each time point]/[value on day 1]) × 100.
Day 1 is defined as the day of application of the skin patch.
1
Target verruca vulgaris lesions having petechiae were subjected to analysis.