TABLE 4.
Disk diffusion results compared with reference broth microdilution MICs for 597 isolates of P. aeruginosa from CF patients
| Antimicrobial(s)a | No. (%) of errors
|
No. of isolates tested | Correlation coefficient (r) | |||
|---|---|---|---|---|---|---|
| Very major | Major | Minor | Total | |||
| Amikacin | 0 | 8 (1.4) | 122 (21.1) | 130 (22.5) | 577 | −0.89 |
| Gentamicin | 1 (0.2) | 0 | 121 (21.0) | 122 (21.1) | 577 | −0.88 |
| Tobramycin | 0 | 1 (0.2) | 87 (15.1) | 88 (15.3) | 577 | −0.89 |
| Ticarcillin | 4 (0.8) | 24 (4.2) | 28 (4.9) | 577 | −0.88 | |
| Ticarcillin-clavulanate | 1 (0.2) | 23 (4.0) | 24 (4.2) | 576 | −0.87 | |
| Piperacillin | 6 (1.0) | 10 (1.7) | 16 (2.8) | 577 | −0.90 | |
| Piperacillin-tazobactam | 4 (0.8) | 6 (1.0) | 11 (1.9) | 576 | −0.90 | |
| Ceftazidime | 6 (1.3) | 1 (0.2) | 74 (12.8) | 82 (14.2) | 576 | −0.91 |
| Aztreonam | 1 (0.2) | 4 (0.7) | 102 (17.7) | 107 (18.6) | 576 | −0.90 |
| Ciprofloxacin | 0 | 0 | 135 (23.4) | 135 (23.4) | 576 | −0.90 |
| Imipenem | 1 (0.2) | 0 | 72 (12.5) | 73 (12.7) | 576 | −0.90 |
| Meropenem | 2 (0.4) | 1 (0.2) | 69 (12.0) | 73 (12.7) | 576 | −0.87 |
| Allb | 25 (0.4) | 78 (1.1) | 782 (11.3) | 889 (12.9) | 6,917 | −0.89 |
a
Ticarcillin-clavulanate, 2 μg/ml; piperacillin-tazobactam, 4 μg/ml.
b
Mean values.