TABLE 7.
Etest MICs compared with reference broth microdilution MICs for 160 mucoid isolates of P. aeruginosa from CF patients
| Antimicrobial(s)a | No. (%) of errors
|
No. of isolates tested | Correlation coefficient (r) | Regression slope | |||
|---|---|---|---|---|---|---|---|
| Very major | Major | Minor | Total | ||||
| Amikacin | 0 | 0 | 28 (18.8) | 28 (18.8) | 149 | 0.88 | 0.80 |
| Gentamicin | 0 | 0 | 52 (35.1) | 52 (35.1) | 148 | 0.86 | 0.81 |
| Tobramycin | 0 | 1 (0.7) | 21 (14.6) | 22 (15.3) | 144 | 0.86 | 1.09 |
| Ticarcillin | 1 (0.7) | 12 (8.8) | 13 (9.5) | 137 | 0.84 | 0.68 | |
| Ticarcillin-clavulanate | 0 | 10 (7.0) | 10 (7.0) | 142 | 0.88 | 0.68 | |
| Piperacillin | 0 | 9 (6.3) | 9 (6.3) | 144 | 0.80 | 0.62 | |
| Piperacillin-tazobactam | 0 | 7 (4.9) | 7 (4.9) | 142 | 0.80 | 0.64 | |
| Ceftazidime | 1 (0.7) | 1 (0.7) | 30 (21.0) | 32 (22.4) | 143 | 0.82 | 0.61 |
| Aztreonam | 1 (0.8) | 1 (0.8) | 21 (16.0) | 23 (17.6) | 131 | 0.87 | 0.64 |
| Ciprofloxacin | 0 | 2 (1.8) | 32 (29.1) | 34 (30.9) | 110 | 0.84 | 0.64 |
| Imipenem | 0 | 3 (2.2) | 10 (7.3) | 13 (9.5) | 137 | 0.88 | 0.65 |
| Meropenem | 0 | 3 (2.5) | 13 (10.7) | 16 (13.2) | 121 | 0.81 | 0.63 |
| Allb | 3 (0.2) | 49 (3.0) | 207 (12.6) | 259 (15.7) | 1,648 | 0.85 | 0.71 |
a
Ticarcillin-clavulanate, 2 μg/ml; piperacillin-tazobactam, 4 μg/ml.
b
Mean values.