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letter
. 2021 Jun 11;1(3):100031. doi: 10.1016/j.xjidi.2021.100031

Table 1.

Different Types of Skin Reactions

Type Irritated Skin Allergic Skin Sensitive Skin Atopic Skin
Pathophysiology Chemical reaction Allergy Neuropathic disorder Atopy
Triggering factors Irritant chemicals Allergens Physicochemical factors Atopens, stress
Affected individuals All Allergic Reactive Atopic
Area Area of application Area of application and beyond Area of application and beyond Widespread
Objective symptoms Erythema Erythema, vesicles Erythema Erythema, vesicles
Subjective symptoms Pain Pruritus Paresthesia Pruritus
Epicutaneous tests Irritative type Eczema Negative Eczema
In vitro tests Specific to irritants Specific to allergens Capsaicin, lactic acid None