Table 7.
Effect of different treatments on osteoblast death markers of HCT-induced osteoclast formation.
Groups | Wnt-5 (ng/mg Protein) |
GSK3βpS9 (µg/mg Protein) |
GSK3β (µg/mg Protein) |
GSK3βpS9/GSK3β | β.Catenin (pg/mg Protein) |
|
---|---|---|---|---|---|---|
Control osteoblast cells (OB) | 2.48 ± 0.23 b | 4.5 ± 0.23 a | 6.8 ± 0.32 a | 0.66 | 1.45 ± 0.005 c | |
OB | CA 13 | 2.58 ± 0.25 b | 4.4 ± 0.21 a | 6.3 ± 0.22 a | 0.69 | 1.32 ± 0.003 a |
OB | CA13/HA50 | 2.85 ± 0.26 c | 4.5 ± 0.11 a | 6.7 ± 0.23 a | 0.67 | 1.42 ± 0.001 bc |
OB | CA13/HA/BER100 | 2.73 ± 0.23 c | 3.9 ± 0.23 a | 6.8 ± 0.19 a | 0.57 | 1.37 ± 0.007 b |
OB | CA13/HA/ME100 | 2.17 ± 0.22 a | 3.7 ± 0.21 a | 6.1 ± 0.23 a | 0.61 | 1.46 ± 0.003 c |
Induction osteoclast cells (OC) | 7.85 ± 0.32 g | 16.2 ± 0.89 e | 15.3 ± 0.89 e | 1.06 | 3.97 ± 0.023 g | |
OC | CA 13% | 5.93 ± 0.23 f | 9.8 ± 1.50 d | 13.0 ± 0.77 d | 0.75 | 3.63 ± 0.015 f |
OC | CA13/HA50 | 5.17 ± 0.25 e | 9.0 ± 0.97 d | 10.9 ± 0.72 c | 0.82 | 2.87 ± 0.009 e |
OC | CA13/HA/BER100 | 3.73 ± 0.29 d | 7.5 ± 1.35 b | 7.6 ± 0.93 b | 0.99 | 1.98 ± 0.008 d |
OC | CA13/HA/ME100 | 4.01 ± 0.10 e | 8.8 ± 1.26 bc | 10.0 ± 0.45 c | 0.88 | 2.12 ± 0.003 d |
Results are the means ± SD in each group. In each column, means with different letters are significantly different with each other, where (a) the lowest mean, means with the same letters are significantly similar at p < 0.05.