Fig. 4.

Interaction between GRFT and PDCoV S protein. (A) Untreated PDCoV virus particles (B) After being treated by 1 μg/mL GRFT, PDCoV virus particles were wrapped in a floccule. Through the interaction of GRFT and S protein, viruses were encapsulated and the spikes of PDCoV were sealed, thus preventing virus entry. (C) GRFT binds directly to PDCoV S protein (●), S1 protein (◼), and S2 protein (▲). PBS control was indicated by the dotted line. The combination ability of GRFT with S1, S, S2 is from strong to weak.