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. 2021 Nov 10;8:762363. doi: 10.3389/fnut.2021.762363

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Copyright © 2021 Lin, Chen, Chen, Lin, Wu, Juan and Chang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GlcN increases hematopoietic stem and progenitor cell compartment. (A) Schematic of hematopoietic hierarchy and critical transcriptional factors and cytokines in myelopoiesis. (B) Schematics of identifying hematopoietic stem cells (HSCs) and multipotent progenitor cells (MPPs). (C) The frequency of HSCs and MPPs in BM after i.p. injection. (D) Schematics of identifying Lin⁻c-Kit⁺Sca-1⁺ cells (LSKs), total myeloid progenitors (MPs, Lin⁻c-Kit⁺Sca-1⁻), common myeloid progenitors (CMPs, Lin⁻c-Kit⁺Sca-1⁻CD34⁺FcRII/III⁻), granulocyte-macrophage progenitors (GMPs, Lin⁻c-Kit⁺Sca-1⁻CD34⁺FcRII/III⁺) and megakaryocyte-erythroid progenitors (MEP, Lin⁻c-Kit⁺Sca-1⁻CD34⁻FcRII/III⁻). (E) The frequency of LSKs, MPs, CMPs, GMPs and MEPs in BM after i.p. injection. The quantified results are presented as the mean ± standard deviation. *P < 0.05; **P < 0.01.