Table 3.
Differences in clinical characteristics between pheochromocytoma patients with and without recurrence.
| Patients | Total patients | Recurrence group | No recurrence group | P value |
|---|---|---|---|---|
| Male | 43% (63/146) | 39% (26/67) | 47% (37/79) | 0.329 |
| Age at diagnosis, y | 36 ± 15.0 | 32.8 ± 15.3 | 39.4 ± 13.3 | 0.007 |
| Follow-up time, y | 7.0 (5.0,9.0) | 6.0 (4.0,9.0) | 8.0 (7.0,9.0) | 0.000 |
| Primary tumor size | 5.8 ± 2.4 | 6.3 ± 2.3 | 5.5 ± 2.5 | 0.048 |
| Tumor size≥5cm | 64% (86/135) | 75% (50/67) | 46% (36/79) | 0.000 |
| Gene mutation | 33% (42/126) | 39% (21/53) | 29% (21/73) | 0.067 |
| SDHB | 6% (8/126) | 9% (5/53) | 4% (3/73) | 0.226 |
| VHL | 8% (10/126) | 13% (7/53) | 4% (3/73) | 0.062 |
| RET | 13% (19/126) | 11% (6/53) | 18% (13/73) | 0.315 |
| MAX | 2% (2/126) | 4% (2/53) | 0% (0/73) | 0.090 |
| Tumor site | ||||
| Left adrenal gland | 41% (59/146) | 45% (29/67) | 38% (30/79) | 0.515 |
| Right adrenal gland | 40% (60/146) | 40% (27/67) | 41% (32/79) | 0.857 |
| Bilateral adrenal glands | 16% (23/146) | 15% (10/67) | 16% (13/79) | 0.800 |
| Multiple primary tumors | 18% (27/146) | 16% (11/67) | 20% (16/79) | 0.552 |
| Laparotomy | 25% (34/136) | 40% (24/60) | 13% (10/76) | 0.000 |
| Capsular invasion | 9% (12/130) | 15% (8/52) | 5% (4/78) | 0.064 |
| Vascular tumor embolus | 8% (11/130) | 12% (6/52) | 6% (5/78) | 0.303 |
| Ki-67 count | 1% (1%,2%)) | 2% (1%, 5%) | 1% (1%,2%) | 0.005 |
| Ki-67 count ≥3% | 22% (24/108) | 38% (15/39) | 13% (9/69) | 0.002 |
Bold values indicate significant P values.