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. 2021 Dec 10;342:388–399. doi: 10.1016/j.jconrel.2021.12.008

Table 1.

Routes of administration and vaccine (RVG-saRNA or Rabipur) doses used to immunize BALB/c mice.

Vaccine Route of administration Dose Dose volume
saRNA (formulated in LNPs, PNPs or SLNs) IM 0.15 μg 50 μL
ID 0.15 μg 20 μL
IN 1.5 μg 50 μL
Rabipur IM 2% HD 50 μL
ID 2% HD 20 μL
IN 5% HD 50 μL

saRNA: self-amplifying RNA; LNPs: lipid nanoparticles, PNPs: polymeric nanoparticles; SLNs: solid-lipid nanoparticles; IM: intramuscular; ID: intradermal; IN: intranasal; HD: human dose.