Table 1.
Baseline data of patients according to cognitive functions.
| Characteristics | All patients (n = 416) | Non-PSCI (n = 164) | PSCI (n = 252) | p |
|---|---|---|---|---|
| Age, years | 64.6 ± 6.9 | 64.3 ± 7.1 | 64.8 ± 6.7 | 0.468 |
| Gender, male, n (%) | 248 (59.6) | 96 (58.5) | 153 (60.7) | 0.658 |
| Education, years | 9.5 ± 1.9 | 9.6 ± 2.1 | 9.4 ± 1.8 | 0.301 |
| BMI, kg/m2 | 24.2 ± 1.6 | 24.1 ± 1.5 | 24.3 ± 1.7 | 0.220 |
| Admission NIHSS | 6 (3-8) | 6 (3-7) | 6 (3-8) | 0.712 |
| Vascular risk factors,n(%) | ||||
| HP | 207 (49.8) | 80 (48.8) | 127 (50.4) | 0.747 |
| DM | 122 (29.3) | 47 (28.7) | 75 (29.8) | 0.809 |
| HLP | 160 (38.5) | 61 (37.2) | 99 (39.3) | 0.668 |
| AF | 36 (8.7) | 15 (9.1) | 21 (8.3) | 0.628 |
| CHD | 85 (20.4) | 33 (20.1) | 52 (20.6) | 0.849 |
| Current smoking | 128 (30.8) | 50 (30.5) | 78 (31.0) | 0.920 |
| Current drinking | 149 (35.8) | 59 (36.0) | 90 (35.7) | 0.957 |
| TOAST classification,n(%) | ||||
| Large-artery atherosclerosis | 255 (61.3) | 99 (60.4) | 156 (62.0) | 0.753 |
| Small vessel occlusion | 63 (15.1) | 24 (14.6) | 39 (15.5) | 0.815 |
| Cardioembolism | 45 (10.8) | 19 (11.6) | 26 (10.3) | 0.684 |
| Other cause | 29 (7.0) | 12 (7.3) | 17 (6.7) | 0.823 |
| Undetermined | 24 (5.8) | 10 (6.1) | 14 (5.6) | 0.817 |
| Clinical laboratory tests | ||||
| Leukocyte, 109/L | 7.1 ± 2.0 | 6.9 ± 1.8 | 7.2 ± 2.1 | 0.133 |
| Hemoglobin, g/L | 128.4 ± 12.1 | 129.6 ± 13.1 | 127.7 ± 11.5 | 0.120 |
| CRP, mg/L | 4.2 ± 1.1 | 4.1 ± 1.0 | 4.3 ± 1.1 | 0.061 |
| Galectin-3, ng/mL | 7.0 ± 2.0 | 4.9 ± 1.6 | 8.4 ± 2.3 | <0.001 |
Abbreviations: PSCI: poststroke cognitive impairment; BMI: body mass index; NHISS: National Institute of Health Stroke Scale; HP: hypertension; DM: diabetes mellitus; HLP: hyperlipidemia; AF: atrial fibrillation; CHD: coronary heart disease; TOAST: Trial of ORG 10172 in Acute Stroke Treatment; CRP: C–reactive protein.