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CBP HAT domain contributes to Zta coactivation. HeLa cells were cotransfected with 1 μg of BZLF1-luciferase reporter plasmid and expression plasmids for Zta, CBPwt, CBPΔH, CBPΔN, CBPΔNΔH, or the pCMV4 control vector as indicated in the figure. Luciferase units were expressed as fold activation. Values are the averages of at least three independent transfections.
