TABLE 2.
Comparison of results of NASBA for IE mRNA, assays for antigenemia, DNAemia, and viremia, and NASBA for pp67 mRNA
| HCMV assay results | No. (%) of blood samples
|
Pa | ||
|---|---|---|---|---|
| IE mRNA positive | IE mRNA negative | Total | ||
| Antigenemia assay positive | 98 (18.9) | 24 (4.6) | 122 (23.5) | |
| Antigenemia assay negative | 68 (13.1) | 328 (63.4) | 396 (76.5) | <0.0001 |
| Total | 166 (32.0) | 352 (68.0) | 518 | |
| DNAemia assay positive | 113 (21.7) | 24 (4.6) | 137 (26.3) | |
| DNAemia assay negative | 54 (10.4) | 329 (63.3) | 383 (73.7) | <0.0001 |
| Total | 167 (32.1) | 353 (67.9) | 520 | |
| Viremia assay positive | 25 (5.2) | 0 | 25 (5.2) | |
| Viremia assay negative | 131 (27.0) | 329 (67.8) | 460 (94.8) | <0.0001 |
| Total | 156 (32.2) | 329 (67.8) | 485 | |
| NASBA for pp67 mRNA positive | 30 (5.9) | 2 (0.4) | 32 (6.3) | |
| NASBA for pp67 mRNA negative | 134 (26.2) | 345 (67.5) | 479 (93.7) | <0.0001 |
| Total | 164 (32.1) | 347 (67.9) | 511 | |
a
Concordant versus discordant results (pearson chi-square test).