Table 1.
The RNA interactors of murine cGAS predicted by catRAPID omics (version 2.0).
| RNA ID | Gene Name | Interaction Propensity | Z-score | RBP Propensity | RNA-Binding Domains | RNA-Binding Motifs | Conserved Interactions | Ranking | |
|---|---|---|---|---|---|---|---|---|---|
| protein-coding RNAs | ENSMUST00000000080 | Kruppel-like Factor 6 (Klf6) | 88.83 | 1.73 | 0.5 | 1 | 0 | 0/0 | 0.405431 |
| ENSMUST00000000291 | max binding protein (Mnt) | 73.94 | 1.34 | 0.5 | 1 | 0 | 0/0 | 0.389061 | |
| ENSMUST00000000579 | sex determining region Y-box 9 (Sox9) | 56.82 | 0.89 | 0.5 | 1 | 0 | 0/0 | 0.37024 | |
| ENSMUST00000000619 | chloride channel, voltage-sensitive 4 (Clcn4) | 74.44 | 1.35 | 0.5 | 1 | 0 | 0/0 | 0.389611 | |
| ENSMUST00000000724 | K (lysine) acetyltransferase 2B (Kat2b) | 61.09 | 1 | 0.5 | 1 | 0 | 0/0 | 0.374934 | |
| long noncoding RNAs | ENSMUST00000047876 | Gm10710 | 45.58 | 0.59 | 0.5 | 1 | 0 | 0/0 | 0.357883 |
| ENSMUST00000052189 | B230317F23Rik | 49.89 | 0.7 | 0.5 | 1 | 0 | 0/0 | 0.362621 | |
| ENSMUST00000097612 | Gm10545 | 49.12 | 0.68 | 0.5 | 1 | 0 | 0/0 | 0.361774 | |
| ENSMUST00000098303 | Gm9934 | 42.98 | 0.52 | 0.5 | 1 | 0 | 0/0 | 0.355024 | |
| ENSMUST00000100713 | Gm10384 | 41.97 | 0.49 | 0.5 | 1 | 0 | 0/0 | 0.353914 | |
| small noncoding RNAs | ENSMUST00000082459 | Gm23627 | 25.98 | 0.07 | 0.49 | 1 | 0 | 0/0 | 0.333001 |
| ENSMUST00000082490 | Gm22749 | 28.99 | 0.15 | 0.49 | 1 | 0 | 0/0 | 0.33631 | |
| ENSMUST00000082508 | Gm26225 | 27.07 | 0.1 | 0.49 | 1 | 0 | 0/0 | 0.3342 | |
| ENSMUST00000082509 | Gm26226 | 36.2 | 0.34 | 0.49 | 1 | 0 | 0/0 | 0.344237 | |
| ENSMUST00000082534 | Gm25081 | 25.39 | 0.06 | 0.49 | 1 | 0 | 0/0 | 0.332353 |
Table summarization of the top 5 predicted coding-RNA interactors (RNA ID and Gene Name) of murine-cGAS by catRAPID omics (version 2.0). The table shows Z-scores (interaction propensity normalization relative to experimental cases), discriminative ability (relative to training sets), interaction strength (enrichment relative to random interactions), the presence of RNA-binding domains, and RNA motifs. RNAs were ranked by the score, which is the sum of three individual values: 1) catRAPID normalized propensity, 2) RBP propensity and 3) presence of known RNA-binding motifs. The full score is 1.