Table 2.
The RNA interactors of human cGAS predicted by catRAPID omics (version 2.0).
| RNA ID | Gene Name | Interaction Propensity | Z-score | RBP Propensity | RNA-Binding Domains | RNA-Binding Motifs | Conserved Interactions | Ranking | |
|---|---|---|---|---|---|---|---|---|---|
| protein-coding RNAs | ENST00000078429 | G protein subunit alpha 11 (GNA11) | 57.38 | 0.9 | 0.35 | 1 | 0 | 0/0 | 0.320855 |
| ENST00000169298 | ST6 beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) | 56.82 | 0.89 | 0.35 | 1 | 0 | 0/0 | 0.32024 | |
| ENST00000170168 | RNA exonuclease 1 homolog (REXO1) | 59.47 | 0.96 | 0.35 | 1 | 0 | 0/0 | 0.323153 | |
| ENST00000174618 | MAX network transcriptional repressor (MNT) | 60.79 | 0.99 | 0.35 | 1 | 0 | 0/0 | 0.324604 | |
| ENST00000193322 | osteoclastogenesis associated transmembrane protein 1 (OSTM1) | 54.06 | 0.81 | 0.35 | 1 | 0 | 0/0 | 0.317205 | |
| long noncoding RNAs | ENST00000242109 | KIAA0087 | 24.68 | 0.04 | 0.35 | 1 | 0 | 0/0 | 0.284905 |
| ENST00000309874 | AC020659.1 | 19.83 | -0.09 | 0.35 | 1 | 0 | 0/0 | 0.279573 | |
| ENST00000316786 | C9orf106 | 21.42 | -0.05 | 0.35 | 1 | 0 | 0/0 | 0.281321 | |
| ENST00000325390 | AC018865.2 | 20.01 | -0.09 | 0.35 | 1 | 0 | 0/0 | 0.279771 | |
| ENST00000329618 | B3GALT5-AS1 | 20.99 | -0.06 | 0.35 | 1 | 0 | 0/0 | 0.280849 | |
| small noncoding RNAs | ENST00000347538 | MIR133A2 | 4.53 | -0.49 | 0.35 | 1 | 0 | 0/0 | 0.262753 |
| ENST00000362117 | MIR16-2 | 6.2 | -0.45 | 0.35 | 1 | 0 | 0/0 | 0.264589 | |
| ENST00000362317 | MIR365B | 7.6 | -0.41 | 0.35 | 1 | 0 | 0/0 | 0.266128 | |
| ENST00000362349 | RNU6-500P | 6.08 | -0.45 | 0.35 | 1 | 0 | 0/0 | 0.264457 | |
| ENST00000362356 | RNU6-50P | 5.19 | -0.48 | 0.35 | 1 | 0 | 0/0 | 0.263478 |
Table summarization of the top 5 predicted coding-RNA interactors (RNA ID and Gene Name) of murine-cGAS by catRAPID omics (version 2.0). The table shows Z-scores (interaction propensity normalization relative to experimental cases), discriminative ability (relative to training sets), interaction strength (enrichment relative to random interactions), the presence of RNA-binding domains, and RNA motifs. RNAs were ranked by the score, which is the sum of three individual values: 1) catRAPID normalized propensity, 2) RBP propensity and 3) presence of known RNA-binding motifs. The full score is 1.