Table 3.
Segment-based diagnostic accuracy results of each reader using color-coded virtual non-calcium (VNCa) images for the assessment of bone marrow edema (BME) extent in vertebral bodies
| Sensitivity | Specificity | PPV | NPV | Accuracy | |
|---|---|---|---|---|---|
| Overall |
1847/2210 (0.84) [0.82–0.85] |
12135/12390 (0.98) [0.98–0.98] |
1847/2102 (0.88) [0.87–0.89] |
12135/12498 (0.97) [0.97–0.97] |
13982/14600 (0.96) [0.95–0.96] |
| Reader 1 |
409/442 (0.93) [0.90–0.95] |
2454/2478 (0.99) [0.98–0.99] |
409/433 (0.94) [0.92–0.96] |
2454/2487 (0.99) [0.98–0.99] |
2863/2920 (0.98) [0.97–0.99] |
| Reader 2 |
384/442 (0.87) [0.83–0.90] |
2417/2478 (0.98) [0.97–0.98] |
384/445 (0.86) [0.83–0.89] |
2417/2475 (0.98) [0.97–0.98] |
2801/2920 (0.96) [0.95–0.97] |
| Reader 3 |
353/442 (0.80) [0.76–0.84] |
2421/2478 (0.98) [0.97–0.98] |
353/410 (0.86) [0.83–0.89] |
2421/2510 (0.96) [0.96–0.97] |
2774/2920 (0.95) [0.94–0.96] |
| Reader 4 |
352/442 (0.80) [0.76–0.83] |
2424/2478 (0.98) [0.97–0.98] |
352/406 (0.87) [0.83–0.90] |
2424/2514 (0.96) [0.96–0.97] |
2776/2920 (0.95) [0.94–0.96] |
| Reader 5 |
349/442 (0.79) [0.75–0.83] |
2419/2478 (0.98) [0.97–0.98] |
349/408 (0.86) [0.82–0.88] |
2419/2512 (0.96) [0.96–0.97] |
2768/2920 (0.95) [0.94–0.96] |
Statistical measures are presented as fractions and decimal values (round brackets), with 95% confidence intervals in square brackets
PPV positive predictive value, NPV negative predictive value