Table 1.
Summary baseline clinicopathological characteristics of the study cohort. The p-values are presented for an intergroup comparison between progressors and non-progressors performed using the Mann-Whitney U test. AS, active surveillance; PSA, prostate-specific antigen
Parameter | Total cohort (n = 64) | Progressors (n = 27) | Non-progressors (n = 37) | p-value |
---|---|---|---|---|
Age, years | 67 (60–69) | 66 (60–69) | 67 (61–69) | 0.9218 |
PSA, ng/mL | 5.6 (3.6–7.7) | 7.0 (5.2–8.7) | 5.0 (3.17–6.9) | 0.0102 |
Gland volume, mL | 45.0 (33.0–63.8) | 45.0 (29.0–52.0) | 45.0 (36.6–66.2) | 0.1851 |
PSA density | 0.11 (0.08–0.19) | 0.17 (0.11–0.27) | 0.09 (0.06–0.16) | 0.0024 |
AS follow-up, mo | 46 (35–52) | 43 (24–49) | 47 (44–60) | 0.0093 |
Biopsy grade group 1 (3 + 3 = 6), n | 51 (78%) | 23 (85%) | 28 (74%) | - |
Biopsy grade group 2 (3 + 4 = 7), n | 14 (22%) | 4 (15%) | 10 (26%) | |
Target lesion in the peripheral zone, n | 46 (70%) | 17 (63%) | 29 (76%) | - |
Target lesion in the transition zone, n | 19 (30%) | 10 (27%) | 9 (24%) |