Table 2.
Diagnostic accuracy in proximal stenosis of ≥ 50% DS
| Total | TP | TN | FP | FN | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Pos-LR | Neg-LR | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Per patient | 1060 | 296 | 536 | 217 | 11 | 96.4 (93.5–98.1) | 71.2 (67.8–74.4) | 57.7 (54.9–60.5) | 98.0 (96.5–98.9) | 3.34 (2.98–3.75) | 0.05 (0.03–0.09) |
| Per segment | |||||||||||
| -All segments(with non-evaluable) | 4239 | 460 | 3342 | 391 | 46 | 90.9 (88.6–93.2) | 89.5 (88.5–90.5) | 54.1 (50.6–57.4) | 98.6 (98.2–99.0) | 8.68 (7.87–9.57) | 0.10 (0.08–0.13) |
| Evaluable segments CTA | Total | TP | TN | FP | FN | Non-evaluable segments CTA | Total | ICA positive | ICA negative | ICA ND | |
| -Proximal RCA | 971 | 146 | 736 | 73 | 16 | -Proximal RCA | 89 | 13 | 76 | 0 | |
| -Left main | 1028 | 29 | 934 | 57 | 8 | -Left main | 31 | 10 | 21 | 0 | |
| -Proximal LAD | 992 | 120 | 706 | 150 | 16 | -Proximal LAD | 68 | 26 | 41 | 1 | |
| -Proximal rCX | 977 | 82 | 778 | 111 | 6 | -Proximal rCX | 83 | 32 | 50 | 1 | |
Diagnostic accuracy of CTA as compared with invasive coronary angiography for the detection of > 50% DS coronary lesions. Values between parentheses represent the outer bounds of the 95% confidence interval. Abbreviations: TP, true positives; TN, true negatives; FN, false negatives; FP, false positives; PPV, positive predictive value; NPV, negative predictive value; Pos-LR, positive likelihood ratio; Neg-LR, negative likelihood ratio; ICA, invasive coronary angiography; RCA, right coronary artery; LAD, left anterior descending artery; rCX, ramus circumflex; ND, non-evaluable