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. 2021 Dec 9;14:22. doi: 10.1007/s40820-021-00761-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Change of dissolved O₂ in 4T1 cells treated with different formulations. b CLSM images and c flow histogram of cellular hypoxia of 4T1 cells incubated with different formulations using a hypoxia probe. d Cell viability of 4T1 cells treated with m_eTG, m_eTC, m_eTGC, and m_eTGCT with various GOX/CPO concentrations under 808 + 635 nm lasers irradiation. Cell viability of 4T1 cells incubated with various formulations in e 21% O₂ condition and f 2% O₂ condition with/without laser irradiation. g Live/dead staining images and h cell apoptosis of 4T1 cells after various treatments for 4 h (***p < 0.001, **p < 0.01, *p < 0.05, n = 5)