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. 2021 Oct 14;70(12):2947–2956. doi: 10.2337/db21-0198

Figure 6.

Figure 6

AD: Plasma glucose concentration (A), SRM A-peptide (A-chain) and B-peptide measurement (B-chain) (B), SRM quantification of processed Cα-peptide and nonprocessed CαK-peptide (C), and ratio of CαK-peptide to Cα-peptide (ratio of 74-AA proinsulin surrogate to mature insulin surrogate) (D) after an overnight fast (FG) (62.9 ± 1.1 years) (male n = 3; female n = 4) and 2h-IVG (57.9 ± 5.3 years) (male n = 9; female n = 6) infusion (continuous glucose infusion to maintain steady-state FG level + 98 mg/dL for 2 h). *P < 0.05.