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. 2021 Nov 26;12:752393. doi: 10.3389/fmicb.2021.752393

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Copyright © 2021 Zhang, Fang, Li, Zhang, Lai, Xu, Liu, Xiong, Li, Zhang, Wan, Xu, Chen, Zhang, Ma and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Heatmap and (B,C) ternary diagram profiles showing the dominant OTU differences in fecal microbiota of male and female healthy controls and patients with end-stage renal disease caused by IgA nephropathy (ESRD-IgAN) or type-2 diabetes mellitus (ESRD-T2DM). FHC, FESRD-IgAN, and FESRD-T2DM indicate female healthy control and patients with end-stage renal disease caused by IgA nephropathy (ESRD-IgAN) or type-2 diabetes mellitus (ESRD-T2DM), respectively. MHC, MESRD-IgAN, and MESRD-T2DM indicate male healthy control and patients with ESRD-IgAN, or ESRD-T2DM, respectively.