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. 2021 Nov 24;20:15330338211045506. doi: 10.1177/15330338211045506

Figure 3.

Figure 3.

Increased CTEN expression suppression cell growth, migration, and tube formation in vitro and in vivo. (A) The CCK-8 kit assay showing CTEN overexpression suppressed the proliferation of HUVEC cells. n = 5. (B) CTEN overexpression inhibited migration of HUVEC cells. n = 5. (C) CTEN overexpression decreased tube formation of HUVEC cells. n = 5. (D) CTEN overexpression suppressed proliferation of MCF7 cells. n = 5. (E) CTEN overexpression decreased migration of MCF7 cells. n = 5. (F) CTEN overexpression decreased tumor growth in nude mice. n = 8. *P < .05, **P < .01.

Abbreviations: CCK-8, cell counting kit-8; CTEN, C-terminal tensin-like; HUVEC, human umbilical vein endothelial cell.