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. 2021 Nov 26;11:778754. doi: 10.3389/fonc.2021.778754

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Copyright © 2021 Rana, Chauhan, Gautam, Kulkarni, Banarjee, Chugh, Chhabra, Acharya, Kalra, Gupta, Jain and Ganguly

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic analysis using iTRAQ labelling. (A) Venn diagram indicating the protein identified in our study and those reported in Vesiclepedia. (B) Venn diagram indicating proteins identified in the present study along with the previously reported in Vesiclepedia from exosomes in glioma. (C) pLSDA analysis of replicate runs of each pooled sample. (D) (A–C) Differential expression Analysis volcano plots of log2 (fold change) VS log10 (p value) indicates the proteins (colored in pink) showing statistically significant difference abundance in the different grades of glioma as compared to control.