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Adverse events and costs in the pembrolizumab group and chemotherapy group.
| Medical cost ($) | Pembrolizumab group Grade 3-5 (%) | Placebo group Grade 3-5 (%) | Reference | |
|---|---|---|---|---|
| Nausea | 14.62 | 3.5 | 4 | (15) |
| Anemia | 604.03 | 18.3 | 15.8 | (16) |
| Fatigue | 135.51 | 6.9 | 3.5 | (15) |
| Diarrhea | 5.90 | 5.2 | 3 | (16) |
| Neutropenia | 541.85 | 16 | 12.4 | (15) |
| Vomiting | 14.62 | 4 | 3 | (15) |
| Dyspnea | 343.18 | 4.2 | 5 | (17) |
| Asthenia | 135.51 | 6.7 | 3.5 | (15) |
| Thrombocytopenia | 550.91 | 8.4 | 6.9 | (16) |
