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. 2021 Nov 26;12:756062. doi: 10.3389/fneur.2021.756062

Table 1.

Clinical characteristics, process times, and stroke etiologies of the study population.

Telestroke (n = 104) Stroke center (n = 48) p-value
Demographics
Gender, male, n (%) 52 (50) 24 (50) 1.0
Age, years, mean ±σ 73.3 ± 12.7 75.5 ± 11.4 0.32
Initial stroke severity, median (IQR)
NIHSS 8 (9) 6.5 (6.8) 0.28
ASPECTS 10 (1) 10 (1) 0.99
Clinical baseline values, x¯ ±σ
Serum glucose, mmol/L 7.1 ± 2.7 7.1 ± 2.4 0.85
Initial systolic blood pressure 167 ± 31.3 170 ± 34 0.55
Initial diastolic blood pressure 87 ± 27 89 ± 21.5 0.36
Pre-IVT systolic blood pressure 160 ± 29 156 ± 26 0.24
Pre-IVT diastolic blood pressure 83 ± 19 81 ± 15.8 0.55
Vascular risk factors, n (%)
Previous ischemic stroke 23 (22.1) 13 (27.1) 0.50
Arterial hypertension 92 (88.5) 44 (91.7) 0.55
Diabetes mellitus type II 44 (42.3) 23 (47.9) 0.52
Hyperlipidemia 78 (75) 39 (81.3) 0.40
Atrial fibrillation 29 (27.9) 15 (31.3) 0.67
Smoking 17 (16.3) 5 (12.5) 0.54
Pre-medication, n (%)
Antiplatelet therapy 44 (42.7) 14 (29.2) 0.11
Anticoagulation 3 (2.9) 4 (8.3) 0.21
Large vessel occlusion, n (%)
Any 8 (7.7) 20 (41.7) <0.0001
Terminal internal carotid artery 3 (2.9) 4 (8.3)
Middle cerebral artery 4 (3.9) 12 (25)
Basilar artery 0 (0) 1 (2.1)
Other 1 (1) 3 (6.3)
Process times, median (IQR)
Door-to-imaging, min 17 (24) 18 (20) 0.40
Door-to-needle, min 74 (57) 67 (39.5) 0.20
Onset-to-treatment, min 210 (45) 228 (58) 0.02
Door-to-consult, min 18 (23)
Teleconsult duration, min* 10 (13)
Stroke etiology, n (%)
Toast classification <0.0001
Large-artery atherosclerosis 8 (7.7) 20 (41.7)
Small-vessel occlusion 9 (8.7) 4 (8.3)
Cardioembolism 20 (19.2) 17 (35.4)
Other determined etiology 1 (1) 1 (2.1)
Undetermined etiology 66 (63.5) 2 (4.2)
Stroke mimics 3 (2.9) - 0.55

σ, standard deviation; x¯, mean; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale.

*

According to data from 42 telestroke patients.