TABLE 3.
CD8 T effector | DNA damage repair | Pan-F-TBRS | Antigen processing machinery | Immune checkpoint | EMT1 | FGFR3-related genes | KEGG discovered histones | Angiogenesis | Fanconi anemia | Cell cycle | DNA replication | Nucleotide excision repair | Homologous recombination | Mismatch repair | EMT2 | EMT3 | WNT target | Cell cycle regulators | m6Ascore | |
CD8 T effector | 1 | –0.06623 | 0.494146 | 0.536072 | 0.598255 | 0.245074 | 0.029818 | 0.240562 | 0.269904 | 0.002989 | 0.082286 | 0.124355 | 0.016115 | 0.063399 | 0.112345 | 0.43682 | 0.198802 | –0.11137 | 0.15242 | 0.10087 |
DNA damage repair | –0.06623 | 1 | 0.024836 | 0.116577 | –0.13442 | 0.011223 | –0.47825 | 0.146823 | –0.12574 | 0.878726 | 0.813629 | 0.824877 | 0.836755 | 0.820814 | 0.820688 | –0.16487 | 0.126626 | 0.309855 | 0.441637 | 0.584229 |
Pan-F-TBRS | 0.494146 | 0.024836 | 1 | 0.438899 | 0.34292 | 0.28936 | –0.05985 | 0.132219 | 0.406115 | 0.066112 | 0.196143 | 0.173792 | 0.092248 | 0.129053 | 0.174611 | 0.549272 | 0.224397 | –0.01538 | 0.184433 | 0.212418 |
Antigen processing machinery | 0.536072 | 0.116577 | 0.438899 | 1 | 0.541629 | 0.187812 | –0.16389 | 0.072601 | 0.167215 | 0.064941 | 0.175006 | 0.281397 | 0.277245 | 0.247106 | 0.274653 | 0.415263 | 0.053926 | –0.13306 | 0.125629 | 0.203783 |
Immune checkpoint | 0.598255 | –0.13442 | 0.34292 | 0.541629 | 1 | 0.356499 | –0.02195 | 0.269656 | 0.068756 | –0.07124 | –0.04095 | 0.043847 | 0.022381 | 0.054325 | 0.058231 | 0.572692 | 0.142592 | –0.24812 | 0.065915 | 0.176486 |
EMT1 | 0.245074 | 0.011223 | 0.28936 | 0.187812 | 0.356499 | 1 | –0.08486 | 0.315416 | 0.016401 | 0.093048 | 0.15701 | 0.110437 | 0.065016 | 0.118769 | 0.119983 | 0.411339 | 0.327001 | –0.02501 | 0.108318 | 0.23616 |
FGFR3-related genes | 0.029818 | –0.47825 | –0.05985 | –0.16389 | –0.02195 | –0.08486 | 1 | –0.03991 | 0.132106 | –0.41741 | –0.40019 | –0.37222 | –0.48137 | –0.43936 | –0.40138 | 0.02771 | 0.006555 | –0.09827 | –0.21446 | –0.39919 |
KEGG discovered histones | 0.240562 | 0.146823 | 0.132219 | 0.072601 | 0.269656 | 0.315416 | –0.03991 | 1 | –0.06394 | 0.250681 | 0.292092 | 0.241739 | 0.119934 | 0.21112 | 0.255154 | 0.262104 | 0.280397 | 0.079615 | 0.237842 | 0.320571 |
Angiogenesis | 0.269904 | –0.12574 | 0.406115 | 0.167215 | 0.068756 | 0.016401 | 0.132106 | –0.06394 | 1 | –0.14645 | –0.01328 | –0.05129 | –0.11277 | –0.15847 | –0.07124 | 0.17815 | 0.284032 | 0.036217 | 0.041086 | –0.03072 |
Fanconi anemia | 0.002989 | 0.878726 | 0.066112 | 0.064941 | –0.07124 | 0.093048 | –0.41741 | 0.250681 | –0.14645 | 1 | 0.833289 | 0.803697 | 0.708281 | 0.847198 | 0.793349 | –0.10502 | 0.182189 | 0.282467 | 0.481197 | 0.61288 |
Cell cycle | 0.082286 | 0.813629 | 0.196143 | 0.175006 | –0.04095 | 0.15701 | –0.40019 | 0.292092 | –0.01328 | 0.833289 | 1 | 0.821026 | 0.719566 | 0.751727 | 0.824546 | 0.004818 | 0.339261 | 0.404269 | 0.545496 | 0.660695 |
DNA replication | 0.124355 | 0.824877 | 0.173792 | 0.281397 | 0.043847 | 0.110437 | –0.37222 | 0.241739 | –0.05129 | 0.803697 | 0.821026 | 1 | 0.839333 | 0.868693 | 0.915835 | 0.000474 | 0.168178 | 0.170521 | 0.345734 | 0.481268 |
Nucleotide excision repair | 0.016115 | 0.836755 | 0.092248 | 0.277245 | 0.022381 | 0.065016 | –0.48137 | 0.119934 | –0.11277 | 0.708281 | 0.719566 | 0.839333 | 1 | 0.799102 | 0.852096 | 0.00519 | 0.100386 | 0.145031 | 0.294501 | 0.518847 |
Homologous recombination | 0.063399 | 0.820814 | 0.129053 | 0.247106 | 0.054325 | 0.118769 | –0.43936 | 0.21112 | –0.15847 | 0.847198 | 0.751727 | 0.868693 | 0.799102 | 1 | 0.84498 | 0.022523 | 0.072592 | 0.123744 | 0.352855 | 0.533086 |
Mismatch repair | 0.112345 | 0.820688 | 0.174611 | 0.274653 | 0.058231 | 0.119983 | –0.40138 | 0.255154 | –0.07124 | 0.793349 | 0.824546 | 0.915835 | 0.852096 | 0.84498 | 1 | 0.046523 | 0.196592 | 0.158169 | 0.384789 | 0.595633 |
EMT2 | 0.43682 | –0.16487 | 0.549272 | 0.415263 | 0.572692 | 0.411339 | 0.02771 | 0.262104 | 0.17815 | –0.10502 | 0.004818 | 0.000474 | 0.00519 | 0.022523 | 0.046523 | 1 | 0.155017 | –0.16645 | 0.035051 | 0.174384 |
EMT3 | 0.198802 | 0.126626 | 0.224397 | 0.053926 | 0.142592 | 0.327001 | 0.006555 | 0.280397 | 0.284032 | 0.182189 | 0.339261 | 0.168178 | 0.100386 | 0.072592 | 0.196592 | 0.155017 | 1 | 0.315586 | 0.322768 | 0.408854 |
WNT target | –0.11137 | 0.309855 | –0.01538 | –0.13306 | –0.24812 | –0.02501 | –0.09827 | 0.079615 | 0.036217 | 0.282467 | 0.404269 | 0.170521 | 0.145031 | 0.123744 | 0.158169 | –0.16645 | 0.315586 | 1 | 0.386595 | 0.329243 |
Cell cycle regulators | 0.15242 | 0.441637 | 0.184433 | 0.125629 | 0.065915 | 0.108318 | –0.21446 | 0.237842 | 0.041086 | 0.481197 | 0.545496 | 0.345734 | 0.294501 | 0.352855 | 0.384789 | 0.035051 | 0.322768 | 0.386595 | 1 | 0.512414 |
m6Ascore | 0.10087 | 0.584229 | 0.212418 | 0.203783 | 0.176486 | 0.23616 | –0.39919 | 0.320571 | –0.03072 | 0.61288 | 0.660695 | 0.481268 | 0.518847 | 0.533086 | 0.595633 | 0.174384 | 0.408854 | 0.329243 | 0.512414 | 1 |