Table 2.

Prevalence of PBC, PSC, and AIH in 2015

Category	Subcategory	PBC			PSC			AIH
		n	Prevalence	95% CI	n	Prevalence	95% CI	n	Prevalence	95% CI
Population	–	1299	39.62	37.50–41.74	353	10.77	9.65–11.88	1116	34.04	32.06–36.02
Latitude	50°-	83	28.16	21.88–34.44	27	9.71	5.87–13.55	93	32.19	25.38–39.00
	51°-	381	30.59	27.50–33.69	141	10.61	8.84–12.38	382	29.78	26.76–32.79
	52°-	84	27.29	21.44–33.15	30	9.90	6.29–13.50	88	29.00	22.89–35.10
	53°-	161	42.01	35.51–48.51	34	8.55	5.64–11.45	143	37.20	31.04–43.37
	54°-	153	63.86	53.70–74.02	27	11.41	7.09–15.74	98	42.69	34.10–51.30
	55°-	195	49.79	42.02–57.56	40	10.46	7.01–13.91	148	40.47	33.02–47.93
	56°-	103	60.95	48.53–73.36	18	10.63	5.67–15.58	71	41.00	31.17–50.82
	57°-	129	61.08	50.11–72.05	34	16.70	10.77–22.63	88	39.11	30.44–47.78
	Missing	10	37.40	15.06–59.74	2	8.51	0.00–19.85	5	18.50	3.98–33.03
Sex	Male	143	8.82	7.37–10.28	205	13.25	11.43–15.07	283	17.93	15.83–20.04
	Female	1156	69.35	65.36–73.33	148	8.69	7.28–10.09	833	50.36	46.92–53.79
Age	0-9.9	0	0.00	0.00–0.00	1	0.06	0.00–0.18)	2	2.55	0.00–7.43
	10-19.9	0	0.00	0.00–0.00	11	3.64	1.40–5.89	28	9.02	4.34–13.68
	20-29.9	2	0.77	0.00–1.95	33	7.23	4.14–10.32	67	16.74	10.76–22.71
	30-39.9	31	5.88	3.78–7.98	42	8.30	5.72–10.88	82	23.58	14.76–32.40
	40-49.9	121	21.04	17.27–24.82	44	9.09	5.44–12.73	132	28.08	18.51–37.65
	50-59.9	260	52.81	41.85–63.77	67	12.34	9.36–15.32	201	35.66	30.68–40.65
	60-69.9	363	84.44	70.06–98.82	73	15.81	12.07–19.55	279	68.96	55.14–82.77
	70-79.9	344	100.97	89.93–112.02	54	19.14	12.56–25.72	221	66.06	56.93–75.20
	80-89.9	163	84.97	70.48–99.46	26	12.41	7.34–17.49	97	57.29	44.49–70.10
	90+	15	29.64	13.90–45.37	2	3.38	0.00–7.90	7	33.83	0.96–66.69
Deprivation	1 – least	269	38.15	32.99–43.30	13	9.84	6.14–13.53	233	31.40	26.79–36.00
	2	295	43.15	38.50–48.36	88	11.92	9.67–14.69	261	35.87	31.40–40.34
	3	268	39.24	34.82–44.24	83	12.14	9.79–15.05	247	36.30	31.77–40.83
	4	256	41.82	37.00–47.27	70	10.25	8.11–12.96	189	32.09	27.41–36.78
	5 – most	175	40.28	34.74–46.72	64	10.45	8.18–13.36	156	37.31	30.60–44.00
	Missing	36	28.32	20.43–39.27	35	8.06	5.78–11.22	30	27.27	16.52–38.03
Smoking	Smoker	347	48.60	43.04–4.15	41	5.27	3.54–7.00	273	40.01	34.37–45.66
	Ex-smoker	351	52.55	46.96–58.13	60	8.49	6.19–10.80	234	36.33	31.46–41.21
	Never smoker	596	31.43	28.89–33.97	247	14.13	12.34–15.93	595	32.73	29.91–35.57
	Missing	5	10.69	0.61–20.77	5	3.92	0.00–8.14	14	23.31	8.09–38.55

NOTE. Figures are adjusted for latitude, sex, age, Townsend³⁰ deprivation quintile, and smoking status by direct standardization as appropriate. Figures are per 100,000 population with 95% CIs. Deprivation refers to Townsend³⁰ deprivation quintiles. See also Supplementary Table 4 for unadjusted figures.

AIH, autoimmune hepatitis; PBC, primary biliary cholangitis; PSC, primary sclerosing cholangitis; CI, confidence interval.