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. 2021 Dec 7;27(45):7801–7812. doi: 10.3748/wjg.v27.i45.7801

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Volcano plot and heat map of the patients. A: Volcano plot of the 754-microRNA (miRNA) analyzed in inflammatory bowel disease patients. Control group: Crohn’s disease (CD). Threshold x: fold change = 1; Threshold y: P ≤ 0.05; B: Heat map of the 13 significantly different miRNA between the CD and ulcerative colitis patients with a fold-change in expression level greater than 1 relatively to the expression levels in CD patients (8 upregulated and 5 downregulated). miRNA: MicroRNA.