Table 2.
Gene enrichment analysis of decreased microRNAs in ulcerative colitis patients compared with Crohn’s disease patients
|
Pathway
|
P
value
|
FDR
|
| Proteoglycans in cancer | 2.27E-11 | 6.99E-09 |
| FoxO signaling pathway | 2.37E-11 | 3.64E-09 |
| Pathways in cancer | 7.49E-11 | 7.69E-09 |
| Colorectal cancer | 1.25E-07 | 5.51E-06 |
| TGF-β signaling pathway | 1.47E-07 | 4.53E-06 |
| Signaling pathways regulating pluripotency of stem cells | 4.72E-07 | 1.32E-05 |
| Autophagy | 5.58E-07 | 1.32E-05 |
| ErbB signaling pathway | 9.95E-07 | 2.19E-05 |
| mTOR signaling pathway | 3.70E-06 | 7.61E-05 |
| MAPK signaling pathway | 1.66E-05 | 2.22E-04 |
FoxO: Forkhead box protein O; TGF: Transforming growth factor-β; ErbB: Erythroblastic leukemia viral oncogene homolog; mTOR: Mammalian target of rapamycin; MAPK: Mitogen-activated protein kinase; FDR: False discovery rate-adjusted.