Table 2.
Tumor Mean and Median 3DVGR Depending on the Class (1, 2, and 3) and the Period: Pretreatment, During the First 3 Months Undertreatment, and After 3 Months Undertreatment
| Class 1 | Class 2 | Class 3 | Overall Population | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Median | P | Mean | SD | Median | P | Mean | SD | Median | P | Mean | SD | Median | P | |
| Pre-ttt TGR | 6.13 | 5.01 | 5.08 | 6.09 | 7.28 | 3 | 46.89 | 58.8 | 23.15 | 16.30 | 33.75 | 5.10 | ||||
| Under-ttt TGR (within 3 months) | −18.7 | 3.36 | −17.81 | .003 | −0.09 | 1.34 | −1.2 | .000 | 19.16 | 2.73 | 19.16 | .75 | 2.97 | 10.99 | 0.33 | .000 |
| Under-ttt TGR (after the 3 first months) | −0.14 | 0.58 | 0.42 | .003 | 1.81 | 0.43 | 1.24 | .000 | 13.46 | 2.08 | 13.46 | .084 | 4.51 | 5.33 | 1.96 | .000 |
Abbreviations: 3DVGR, 3D volume growth rate; TGR, tumor growth rate; ttt, treatment.
Estimated P-values from the Wilcoxon ranked tests when comparing the pretreatment and undertreatment (in the first 3 months and after 3 months of treatment) 3DVGR depending on the class (1, 2, and 3).