Figure 1. Graphical summary of the key pathological, pathogenic and symptomatic features expressed for the different classes of animal model of PD.

For clarity, all features considered in this review are represented around each model class, but only those expressed are not greyed out. When used, numbers are shown on the top right of the circle they are associated with. (a) Pharmacological models; 1 applies only to the reserpine model. (b) Neuro-/endo-toxin models; 1 applies only to the neurotoxin models. (c) Pesticide toxin models; 1 applies only to the rotenone model, 2 applies only to the paraquat model. (d) α-Synuclein models; 1 applies only to the α-synuclein–AAV model, 2 applies only to the PFF model. (e) Genetic models; 1 applies only to SNCA models. 2 applies only to LRRK2 models. 3 applies only to GBA models.