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. 2021 Dec 8;5(4):NS20210026. doi: 10.1042/NS20210026

Table 3. Summary of the motor features seen in animal models of PD.

Model Motor deficits Responds to L-DOPA Develops L-DOPA-induced dyskinesias
MPTP
6-OHDA
LPS ND ND
Rotenone
Paraquat ND
Permethrin ND
Reserpine ND
Haloperidol ND ND
AAV Inconclusive ND
PFF ND ND
Transgenic
SNCA Inconclusive ND ND
LRRK2 ND
GBA n/a ND

Ticks indicate features reportedly seen in a model, while cross indicates features demonstrated as absent. ND, not documented; Inconclusive, literature shows evidence for and against this feature in the model; n/a, not applicable, due to the lack of motor deficits. For relevant references, please see the main text.