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. 2021 Nov 26;24(12):103517. doi: 10.1016/j.isci.2021.103517

Figure 7.

Figure 7

DON suppresses Akt activation in ISO-induced cardiac hypertrophy

(A) Representative immunoblots of Akt, phospho-Akt(S473), ERK, phosphor-ERK, p38, phosphor-p38, JNK, phospho-JNK, and GAPDH in ISO (15 mg/kg body weight/day)- or control vehicle (saline)- treated C57B/6J mouse hearts subjected to either DON (0.05 mg/kg body weight/day) or saline for 7 days.

(B–E) Quantitative analysis of phospho-Akt, phospho-ERK, phospho-p38, phospho-JNK, and GAPDH in ISO- or control vehicle-treated C57B/6J mouse hearts subjected to either DON (0.05 mg/kg body weight/day) or saline for 7 days (n = 9). ∗p < 0.05: post hoc Tukey's comparison test.